:root{font-family:Inter,system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica Neue,Arial,sans-serif;line-height:1.5;font-weight:400;color:#0f172a;background-color:#f5f7fb;font-synthesis:none;text-rendering:optimizeLegibility;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale}*{box-sizing:border-box}body{margin:0;min-height:100vh;background-color:#f5f7fb}:root{--color-bg: #f8fafc;--color-text: #0f172a;--color-muted: #64748b;--color-border: #e2e8f0;--color-primary: #2563eb;--color-primary-fg: #ffffff;--c-exon: #94a3b8;--c-exon-bg: rgba(148, 163, 184, .2);--c-ref: #2563eb;--c-ref-bg: rgba(37, 99, 235, .15);--c-mut: #dc2626;--c-mut-bg: rgba(220, 38, 38, .15);--c-guide: #059669;--c-guide-bg: rgba(5, 150, 105, .15);--c-pam: #d97706;--c-pam-bg: rgba(245, 158, 11, .3);--c-search: #0ea5e9;--c-search-bg: rgba(14, 165, 233, .1);--c-bystander: #d946ef;--c-bystander-bg: rgba(217, 70, 239, .2);--c-edit-window: #eab308;--c-edit-window-bg: rgba(250, 204, 21, .4);--font-sans: "Inter", system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif;--font-mono: ui-monospace, SFMono-Regular, Menlo, Monaco, Consolas, "Liberation Mono", "Courier New", monospace}.app{max-width:1280px;margin:0 auto;padding:2rem;color:var(--color-text);font-family:var(--font-sans)}.main-content{min-width:0;max-width:100%;overflow:hidden}.app-header{margin-bottom:2rem;border-bottom:1px solid var(--color-border);padding-bottom:1rem}.font-mono{font-family:var(--font-mono)}.header-content{display:flex;justify-content:space-between;align-items:center;flex-wrap:wrap;gap:1rem}.app-header h1{margin:0;font-size:1.5rem;color:var(--color-text)}.main-nav{display:flex;gap:.5rem;align-items:center;flex-wrap:wrap}.main-nav button{margin:0;background:transparent;color:var(--color-muted);padding:.5rem 1rem;border-radius:8px;font-weight:600;border:1px solid transparent;transition:all .2s ease}.nav-toggle{display:none;background:transparent;border:1px solid var(--color-border);border-radius:8px;padding:.5rem;cursor:pointer;color:var(--color-text);margin:0}.nav-toggle svg{display:block}.main-nav button:hover{background:#f1f5f9;color:var(--color-text)}.main-nav button.active{background:#eff6ff;color:var(--color-primary);border-color:#dbeafe}.view-header{display:flex;justify-content:space-between;align-items:flex-start;gap:1rem;margin-bottom:1.5rem}.view-header h2{margin:0;font-size:1.5rem}.view-header .muted{margin-top:.25rem;font-size:.95rem;color:var(--color-muted)}.status-chip{min-width:100px;text-align:center;padding:.35rem .75rem;border-radius:999px;font-weight:600;background:#eef2ff;color:#3730a3;border:1px solid #c7d2fe}label{display:block;font-weight:600;margin-bottom:.35rem}textarea,input,select{width:100%;padding:.55rem .65rem;border-radius:8px;border:1px solid #cbd5f5;font:inherit;background:#fff}textarea{resize:vertical}button{display:inline-flex;align-items:center;justify-content:center;gap:.5rem;border:none;border-radius:10px;background:var(--color-primary);color:var(--color-primary-fg);padding:.75rem 1.5rem;font-weight:600;cursor:pointer;transition:background .15s ease;margin-top:1rem}button:disabled{opacity:.6;cursor:progress}.card{border:1px solid var(--color-border);border-radius:16px;padding:1.5rem;background:#fff;box-shadow:0 20px 40px #0f172a0d;margin-bottom:1.5rem}.error{margin-top:.75rem;color:var(--c-ref);font-weight:600}.summary-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(140px,1fr));gap:1rem}.summary-grid div{background:var(--color-bg);border-radius:10px;padding:.75rem 1rem}.summary-grid span{display:block;font-size:.9rem;color:#475569}.summary-grid strong{font-size:1.4rem}.variant{border:1px solid var(--color-border);border-radius:12px;margin-bottom:.75rem;padding:.75rem 1rem}.variant-header{display:flex;justify-content:space-between;align-items:baseline;gap:1rem}.variant-header span{color:#475569;font-size:.9rem}.candidate{border-top:1px solid var(--color-border);padding:.75rem 0}.candidate:first-of-type{border-top:none}.candidate-header{display:flex;flex-direction:column;gap:.15rem}.badge{display:inline-block;padding:.1rem .4rem;border-radius:999px;background:#e0f2fe;color:#0369a1;font-size:.75rem;margin-right:.35rem}.badge.success{background:#dcfce7;color:#15803d;border:1px solid #86efac}.badge.warning{background:#fef3c7;color:#b45309;border:1px solid #fcd34d}.badge.neutral{background:#f1f5f9;color:#475569;border:1px solid #e2e8f0}.badge.orange{background:#eff6ff;color:#2563eb;border:1px solid #bfdbfe}.badge.danger{background:#fef2f2;color:#b91c1c;border:1px solid #fecaca}.muted{color:var(--color-muted);font-size:.9rem}.muted.small{font-size:.8rem;margin-top:.5rem}.muted.tiny{font-size:.7rem;margin-top:.3rem;text-transform:uppercase;letter-spacing:.05em}pre{background:#0f172a;color:var(--color-border);border-radius:10px;padding:1rem;overflow:auto;font-size:.85rem}.viewer{margin-top:.75rem;max-width:100%;overflow:hidden}.viewer-toolbar{display:flex;align-items:center;gap:.5rem;margin-bottom:.5rem}.viewer-toolbar .spacer{flex:1}.viewer-scroll{overflow-x:auto;border:1px solid var(--color-border);border-radius:10px;background:#fff;max-width:100%}.btn-secondary{background:#f1f5f9;color:var(--color-text);border:1px solid var(--color-border);border-radius:8px;padding:.25rem .5rem;font-weight:600;cursor:pointer;margin-top:0}.btn-secondary:hover{background:var(--color-border)}.legend-sticky{position:sticky;top:.5rem;background:#ffffffe6;-webkit-backdrop-filter:saturate(180%) blur(4px);backdrop-filter:saturate(180%) blur(4px);border:1px solid var(--color-border);padding:.4rem .6rem;border-radius:10px;margin-top:.5rem}.legend{display:flex;flex-wrap:wrap;gap:.65rem;margin-top:.75rem;font-size:.8rem;text-transform:uppercase;letter-spacing:.04em;color:#475569}.legend-title{font-weight:700;color:var(--color-text);margin-right:.35rem}.legend-item{display:inline-flex;align-items:center;gap:.3rem}.legend-swatch{width:.9rem;height:.9rem;border-radius:.2rem;border:1px solid rgba(15,23,42,.2)}.legend-exon{background:var(--c-exon-bg)}.legend-variant-ref{background:var(--c-ref)}.legend-variant-mut{background:var(--c-mut)}.legend-search{background:var(--c-search-bg)}.legend-pam{background:var(--c-pam-bg)}.legend-editing{background:var(--c-edit-window-bg)}.legend-bystander{background:var(--c-bystander-bg)}.legend-guide{background:var(--c-guide-bg)}@media(max-width:1024px){.app{padding:1.5rem}.main-nav button{padding:.4rem .75rem;font-size:.88rem}.protocols-container{grid-template-columns:280px minmax(0,1fr);gap:1.5rem}.protocol-header,.materials-section,.protocol-steps{padding:1.5rem 1.75rem}}@media(max-width:768px){.nav-toggle{display:flex}.main-nav{display:none;width:100%;flex-direction:column;gap:.25rem;padding-top:.75rem;border-top:1px solid var(--color-border);margin-top:.75rem}.main-nav.nav-open{display:flex}.main-nav button{width:100%;text-align:left;padding:.6rem 1rem;font-size:.95rem;border-radius:8px}.main-nav .nav-divider{height:1px;width:100%;margin:.25rem 0}.user-menu{width:100%;justify-content:space-between}.auth-buttons-group{width:100%;flex-direction:column}.auth-buttons-group .auth-button{width:100%;justify-content:center}.header-content{flex-wrap:nowrap}.step-group{gap:1rem}.analysis-run-grid{grid-template-columns:repeat(auto-fit,minmax(200px,1fr))}}@media(max-width:640px){.app{padding:.75rem}.app-header{margin-bottom:1rem;padding-bottom:.75rem}.app-header h1{font-size:1.25rem}.app-header h1 svg{width:24px;height:24px}.view-header{flex-direction:column;gap:.5rem}.view-header h2{font-size:1.25rem}.card{padding:1rem;border-radius:12px}.pill-grid{gap:.4rem}.option-pill{padding:.35rem .75rem;font-size:.8rem}.summary-grid{grid-template-columns:repeat(2,1fr);gap:.5rem}.summary-grid strong{font-size:1.1rem}.matrix-scroll{margin:0 -1rem;padding:0 1rem;border-radius:0;border-left:none;border-right:none}.step-group{flex-direction:column;gap:.75rem}.variant-header{flex-direction:column;gap:.5rem}.variant-input{font-size:.88rem!important}.legend{font-size:.7rem;gap:.5rem}.legend-sticky{padding:.3rem .5rem}}.protocols-container{display:grid;grid-template-columns:340px minmax(0,1fr);gap:2rem;min-height:600px;overflow:hidden}.protocols-sidebar{background:#fff;border:1px solid #e2e8f0;border-radius:14px;padding:1rem;height:fit-content;box-shadow:0 1px 3px #0000000a,0 4px 12px #00000008}.protocol-search-wrap{position:relative}.protocol-search-wrap .protocol-search-icon{position:absolute;left:.7rem;top:50%;transform:translateY(-50%);color:#94a3b8;pointer-events:none;display:flex;align-items:center}.protocol-search-wrap input{padding-left:2.1rem;height:36px;font-size:.85rem;border-radius:10px;border:1px solid #e2e8f0;background:#f8fafc;transition:border-color .15s,background .15s,box-shadow .15s}.protocol-search-wrap input:focus{background:#fff;border-color:#93c5fd;box-shadow:0 0 0 3px #3b82f614;outline:none}.protocol-search-wrap input::placeholder{color:#94a3b8;font-weight:400}.protocol-drafts-toggle{display:flex;align-items:center;gap:.45rem;cursor:pointer;font-size:.78rem;font-weight:500;color:#64748b;-webkit-user-select:none;user-select:none;padding:.35rem .5rem;border-radius:8px;transition:background .15s}.protocol-drafts-toggle:hover{background:#f8fafc}.protocol-drafts-toggle input[type=checkbox]{width:14px;height:14px;accent-color:#d97706;cursor:pointer;flex-shrink:0}.protocol-drafts-warning{margin:.25rem 0 0;font-size:.72rem;color:#92400e;line-height:1.4;padding:.3rem .5rem;background:#fffbeb;border-radius:6px;border:1px solid #fde68a}.protocol-list{list-style:none;padding:0;margin:0}.protocol-list li{margin-bottom:.35rem}.protocol-list li:last-child{margin-bottom:0}.protocol-btn{width:100%;text-align:left;background:transparent;color:#334155;border:1.5px solid transparent;padding:.65rem .75rem;border-radius:10px;cursor:pointer;transition:all .15s ease;margin-top:0;display:flex;flex-direction:column;align-items:flex-start;gap:.2rem;box-shadow:none}.protocol-btn:hover{background:#f1f5f9;border-color:transparent;box-shadow:none;transform:none}.protocol-btn.active{background:#eff6ff;border-color:#bfdbfe;color:#1e40af;box-shadow:none}.protocol-btn.active .protocol-btn-title{color:#1d4ed8}.protocol-btn.active .protocol-btn-desc{color:#3b82f6}.protocol-btn-title{font-weight:600;font-size:.88rem;color:#0f172a;line-height:1.3}.protocol-btn-desc{font-size:.78rem;color:#94a3b8;display:-webkit-box;-webkit-line-clamp:2;-webkit-box-orient:vertical;overflow:hidden;line-height:1.45}.protocol-detail{background:#fff;border:1px solid #e2e8f0;border-radius:16px;padding:0;box-shadow:0 10px 15px -3px #0000000d;overflow:hidden;min-width:0;max-width:100%}.protocol-header{background:linear-gradient(to bottom right,#fff,#f0f9ff);border-bottom:1px solid #e2e8f0;padding:2rem 2.5rem;margin-bottom:0;overflow:hidden}.protocol-detail h2{font-size:1.8rem;color:#0f172a;margin-top:0}.protocol-meta{display:flex;flex-wrap:wrap;gap:1rem;margin-top:1.2rem;color:#475569;font-size:.9rem;align-items:center}.protocol-meta span{display:inline-flex;align-items:center;gap:.4rem;background:#fff9;padding:.2rem .6rem;border-radius:6px;border:1px solid rgba(226,232,240,.6)}.materials-section{background:#fff;padding:2rem 2.5rem;border-bottom:1px solid #e2e8f0;margin:0;border-radius:0;border-left:none;border-right:none;border-top:none;overflow:hidden}.materials-section h3{margin-top:0;font-size:1.2rem;color:#334155}.materials-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(220px,1fr));gap:1rem;margin-top:1.5rem}.material-item{background:#f8fafc;padding:.75rem 1rem;border-radius:8px;border:1px solid #f1f5f9}.material-name{font-weight:700;color:#000}.material-amount{color:var(--color-muted);font-size:.85rem}.protocol-steps{padding:2rem 2.5rem;min-width:0}.protocol-step-section{margin-bottom:2.5rem;min-width:0}.section-title{font-size:1.3rem;color:#1e293b;margin-bottom:1.2rem;padding-bottom:.75rem;border-bottom:2px solid #e2e8f0;display:flex;justify-content:space-between;align-items:baseline}.section-title span.muted{font-size:.9rem;font-weight:400;color:#64748b;background:#f1f5f9;padding:.2rem .6rem;border-radius:999px}.step-item{margin-bottom:.5rem;border-radius:10px;border:1px solid transparent;display:flex;gap:1rem;padding:1rem;transition:background .2s;cursor:pointer;min-width:0}.step-item:hover{background:#f8fafc;border-color:#f1f5f9}.step-item.completed{opacity:.6}.step-number{margin-top:.1rem;min-width:1.5rem;height:1.5rem;border:2px solid var(--color-border);border-radius:50%;display:flex;align-items:center;justify-content:center;cursor:pointer;flex-shrink:0;background:#fff;font-size:.75rem;font-weight:600;color:#64748b;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,monospace}.step-number.checked{background:var(--color-primary);border-color:var(--color-primary);color:#fff}.step-content{line-height:1.6;font-size:1.05rem;min-width:0;flex:1;white-space:pre-line}.step-blocks{display:flex;flex-direction:column;gap:.35rem}.step-paragraph{margin:0}.step-list,.step-sublist{margin:.15rem 0;padding-left:1.35rem}.step-sublist{margin-top:.1rem}.step-list li,.step-sublist li{margin:.15rem 0}.step-note{display:flex;align-items:flex-start;gap:.5rem;margin-top:.75rem;padding:.6rem .8rem;background:#f8fafc;border-left:3px solid #94a3b8;border-radius:4px;font-size:.92rem;color:#475569}.step-note .note-icon{flex-shrink:0;font-size:.9rem}.step-note .note-content{flex:1;min-width:0}.step-note-section{margin-bottom:.5rem}.step-note-section:last-child{margin-bottom:0}.step-idea{display:flex;align-items:flex-start;gap:.5rem;margin-top:.6rem;padding:.6rem .8rem;background:linear-gradient(135deg,#faf5ff,#f3e8ff);border:1px solid #d8b4fe;border-left:3px solid #a855f7;border-radius:6px;font-size:.92rem;color:#6b21a8}.step-idea .idea-icon{flex-shrink:0;font-size:1rem}.step-idea .idea-content{flex:1;min-width:0}.step-idea a{color:#7c3aed}.step-idea a:hover{color:#5b21b6}.step-warning{display:flex;align-items:flex-start;gap:.5rem;margin-top:.75rem;padding:.6rem .8rem;background:#fef2f2;border-left:3px solid #dc2626;border-radius:4px;font-size:.92rem;color:#991b1b}.step-warning .warning-icon{flex-shrink:0;font-size:.9rem}.step-warning .warning-content{flex:1;min-width:0}.highlight-time{color:#15803d;font-weight:700}.highlight-material{color:#000;font-weight:700}@media(max-width:768px){.protocols-container{grid-template-columns:1fr;gap:1rem}.protocols-sidebar{padding:.75rem;border-radius:10px}.protocols-container.has-selection .protocols-sidebar{display:none}.protocol-back-mobile{display:block}.protocol-detail{border-radius:12px}.protocol-header{padding:1.25rem 1rem}.protocol-detail h2{font-size:1.35rem}.protocol-meta{flex-direction:column;align-items:flex-start;gap:.5rem}.materials-section{padding:1.25rem 1rem}.materials-grid{grid-template-columns:1fr}.protocol-steps{padding:1.25rem 1rem}.section-title{font-size:1.1rem;flex-direction:column;align-items:flex-start;gap:.25rem}.step-item{padding:.75rem .5rem;gap:.75rem}.step-content{font-size:.95rem}.step-note,.step-idea,.step-warning{font-size:.85rem;padding:.5rem .6rem}}.protocol-back-mobile{display:none}@media print{.app-header,.protocols-sidebar,.view-header,.protocol-actions,button{display:none!important}.app{padding:0;max-width:none;margin:0}.main-content{padding:0}.protocols-container{display:block;grid-template-columns:1fr;gap:0;min-height:auto}.protocol-detail{border:none;box-shadow:none;padding:0;margin:0}body{color:#000;background:#fff}.muted{color:#444}.materials-section{background:#fff;border:1px solid #ccc;break-inside:avoid}.materials-grid{display:block;column-count:2}.material-item{break-inside:avoid;margin-bottom:.5rem}.step-item{padding:.5rem 0;border-bottom:1px solid #eee;break-inside:avoid}.step-item:hover{background:transparent}.step-number{border-color:#000;min-width:1.25rem;height:1.25rem;font-size:.7rem}.step-number.checked{background:#fff;border-color:#000;color:#000}a{text-decoration:underline;color:#000!important}}.selector-section{display:flex;flex-direction:column;gap:2rem;margin-top:1rem}.selector-header{display:flex;justify-content:space-between;align-items:baseline;margin-bottom:.6rem}.selector-header label{font-weight:600;color:var(--color-text)}.option-pill{border:1px solid var(--color-border);border-radius:999px;background:#fff;padding:.4rem 1rem;cursor:pointer;transition:all .2s ease;display:inline-flex;align-items:center;gap:.5rem;font-size:.9rem;font-weight:500;color:#334155;white-space:nowrap}.option-pill:hover{border-color:#94a3b8;background:#f8fafc}.option-pill.selected{border-color:#2563eb;background:#eff6ff;color:#1e40af;box-shadow:0 0 0 1px #2563eb;font-weight:600}.pill-star{color:#b45309;font-size:.85rem;margin-right:.1rem}.pill-label{white-space:nowrap}.pill-grid{display:flex;flex-wrap:wrap;gap:.5rem}.analysis-run-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(240px,1fr));gap:.75rem}.analysis-run-card{border:1px solid var(--color-border);border-radius:12px;padding:.8rem;background:#f8fafc}.analysis-run-title{display:flex;justify-content:space-between;align-items:center;gap:.5rem}.analysis-run-tags{display:flex;gap:.3rem}.analysis-run-meta{margin-top:.5rem;display:flex;flex-direction:column;gap:.2rem;font-size:.85rem;color:#475569}.clinical-tag{display:inline-flex;align-items:center;justify-content:center;width:1rem;height:1rem;border-radius:999px;font-size:.7rem;color:#b45309;background:#fffbeb;border:1px solid #fbbf24;cursor:help}.variant-badge{display:flex;flex-wrap:wrap;gap:.35rem;margin-top:.4rem;align-items:center}.badge.soft{background:#e0f2fe;color:#0f172a}.matrix-scroll{overflow-x:auto;border:1px solid var(--color-border);border-radius:12px;background:#fff}.results-matrix{width:100%;border-collapse:collapse;min-width:600px}.results-matrix th,.results-matrix td{padding:.75rem 1rem;text-align:center;border-bottom:1px solid var(--color-border)}.results-matrix th.matrix-corner,.results-matrix th.matrix-row-header{text-align:left}.results-matrix th{background:#f8fafc;font-weight:600;font-size:.9rem;color:#475569;position:sticky;top:0;z-index:10}.results-matrix th.matrix-corner{z-index:20;left:0;border-right:1px solid var(--color-border);background:#f1f5f9}.matrix-row-header{position:sticky;left:0;z-index:10;background:#f8fafc;border-right:1px solid var(--color-border);padding-left:.75rem;padding-right:.75rem}.matrix-header-cell{display:flex;flex-direction:column;gap:.2rem}.results-matrix th:not(.matrix-corner):not(.matrix-row-header) .matrix-header-cell{align-items:center}.matrix-pam{font-size:.75rem;color:#94a3b8;font-weight:400}.matrix-cell{text-align:center;cursor:pointer;transition:background .15s}.matrix-cell:hover{background:#f1f5f9}.matrix-cell.selected{background:#eff6ff;box-shadow:inset 0 0 0 2px #3b82f6}.matrix-cell.zero{color:#cbd5e1}.matrix-count{font-weight:600;font-size:1.1rem;color:#0f172a}.matrix-cell.zero .matrix-count{color:#cbd5e1}.matrix-cell.empty{background:#f8fafc;cursor:default}.step-group{display:flex;gap:1.5rem;margin-bottom:2rem}.step-indicator{width:2rem;height:2rem;background:#e0f2fe;color:#0284c7;border-radius:50%;display:flex;align-items:center;justify-content:center;font-weight:700;flex-shrink:0;margin-top:0}.step-title{margin:0 0 .5rem;font-size:1.1rem;color:#0f172a;font-weight:600}.variant-input{width:100%;padding:.75rem;border-radius:8px;border:1px solid #cbd5e1;font-size:1rem;transition:border-color .2s}.variant-input:focus{border-color:#3b82f6;outline:none;box-shadow:0 0 0 2px #3b82f61a}.info-icon-hover:hover{background:#0000001a!important;transform:translateY(-50%) scale(1.1)!important}.option-pill.selected .info-icon-hover:hover{background:#ffffff80!important}.nav-divider{width:1px;height:24px;background:var(--color-border);margin:0 .5rem}.user-menu{display:flex;align-items:center;gap:.75rem}.user-name{font-size:.9rem;font-weight:500;color:var(--color-text);padding:.25rem .75rem;background:#f1f5f9;border-radius:999px}.auth-button{display:inline-flex;align-items:center;gap:.4rem;margin:0;padding:.5rem 1rem;border-radius:8px;font-weight:600;font-size:.9rem;cursor:pointer;transition:all .2s ease}.auth-button.login{background:transparent;color:var(--color-primary);border:1px solid #cbd5e1}.auth-button.login:hover,.auth-button.login.active{background:#eff6ff;border-color:var(--color-primary)}.auth-button.signup{background:var(--color-primary);color:#fff;border:1px solid var(--color-primary)}.auth-button.signup:hover{background:#1d4ed8;border-color:#1d4ed8}.auth-buttons-group{display:flex;align-items:center;gap:.5rem}.auth-button.logout{background:transparent;color:#64748b;border:1px solid #e2e8f0}.auth-button.logout:hover{background:#fef2f2;color:#b91c1c;border-color:#fecaca}.login-container{display:flex;justify-content:center;align-items:center;min-height:60vh;padding:2rem}.login-card{width:100%;max-width:420px;background:#fff;border-radius:20px;box-shadow:0 4px 6px -1px #0000000d,0 20px 40px -10px #0000001a;border:1px solid var(--color-border);overflow:hidden}.login-header{text-align:center;padding:2.5rem 2rem 1.5rem;background:linear-gradient(to bottom,#f8fafc,#fff);border-bottom:1px solid #f1f5f9}.login-header svg{margin-bottom:1rem}.login-header h2{margin:0 0 .5rem;font-size:1.5rem;color:var(--color-text);font-weight:700}.login-subtitle{margin:0;color:var(--color-muted);font-size:.95rem}.login-form{padding:2rem}.form-group{margin-bottom:1.25rem}.form-group label{display:block;margin-bottom:.5rem;font-weight:600;font-size:.9rem;color:#334155}.form-group input{width:100%;padding:.75rem 1rem;border:1.5px solid #e2e8f0;border-radius:10px;font-size:1rem;transition:all .2s ease;background:#fff}.form-group input:focus{outline:none;border-color:var(--color-primary);box-shadow:0 0 0 3px #2563eb1a}.form-group input::placeholder{color:#94a3b8}.login-error{display:flex;align-items:flex-start;gap:.5rem;padding:.75rem 1rem;background:#fef2f2;border:1px solid #fecaca;border-radius:10px;color:#b91c1c;font-weight:500;font-size:.9rem;margin-bottom:1rem}.login-button{width:100%;padding:.9rem;background:linear-gradient(to bottom,#3b82f6,#2563eb);color:#fff;border:none;border-radius:10px;font-size:1rem;font-weight:600;cursor:pointer;transition:all .2s ease;margin-top:.5rem;box-shadow:0 2px 4px #2563eb33}.login-button:hover{background:linear-gradient(to bottom,#2563eb,#1d4ed8);box-shadow:0 4px 8px #2563eb4d;transform:translateY(-1px)}.login-button:active{transform:translateY(0)}.login-button:disabled{background:#94a3b8;cursor:not-allowed;transform:none;box-shadow:none}.spinner{width:16px;height:16px;border:2px solid transparent;border-top-color:#fff;border-radius:50%;animation:spin .8s linear infinite}@keyframes spin{to{transform:rotate(360deg)}}@media(max-width:640px){.login-container{padding:1rem;min-height:50vh}.login-card{border-radius:16px}.login-header{padding:1.5rem 1rem 1rem}.login-form{padding:1.25rem}.analysis-run-grid{grid-template-columns:1fr}.viewer-toolbar{flex-wrap:wrap}}.team-view{max-width:1400px;margin:0 auto;padding:2rem}.team-header{text-align:center;margin-bottom:2.5rem}.team-header h2{font-size:2.5rem;color:#1e293b;margin-bottom:.75rem}.team-header p{font-size:1.1rem;color:#64748b}.team-grid{display:grid;grid-template-columns:repeat(5,1fr);gap:1.5rem;justify-items:center}@media(max-width:1200px){.team-grid{grid-template-columns:repeat(4,1fr)}}@media(max-width:992px){.team-grid{grid-template-columns:repeat(3,1fr)}}@media(max-width:768px){.team-grid{grid-template-columns:repeat(2,1fr);gap:1rem}}@media(max-width:480px){.team-grid{grid-template-columns:1fr}}.team-card{background:#fff;border-radius:12px;box-shadow:0 4px 6px -1px #0000001a,0 2px 4px -2px #0000001a;padding:1.25rem;width:100%;max-width:240px;text-align:center;transition:transform .2s ease,box-shadow .2s ease;border-top:4px solid transparent;display:flex;flex-direction:column}.team-card:hover{transform:translateY(-5px);box-shadow:0 10px 15px -3px #0000001a,0 4px 6px -4px #0000001a}.team-card.dept-neonatology{border-top-color:#0ea5e9}.team-card.dept-neonatology .member-department-badge{background-color:#e0f2fe;color:#0369a1}.team-card.dept-oncology{border-top-color:#8b5cf6}.team-card.dept-oncology .member-department-badge{background-color:#f3e8ff;color:#6d28d9}.team-card.dept-hematology{border-top-color:#f43f5e}.team-card.dept-hematology .member-department-badge{background-color:#ffe4e6;color:#be123c}.team-card.dept-pathology{border-top-color:#10b981}.team-card.dept-pathology .member-department-badge{background-color:#d1fae5;color:#047857}.team-card.dept-immunology{border-top-color:#f59e0b}.team-card.dept-immunology .member-department-badge{background-color:#fef3c7;color:#b45309}.team-card.dept-default{border-top-color:#94a3b8}.team-card.dept-default .member-department-badge{background-color:#f1f5f9;color:#475569}.member-image-container{width:110px;height:110px;margin:0 auto 1rem;border-radius:50%;overflow:hidden;border:3px solid #f1f5f9;box-shadow:0 2px 4px #0000000d}.member-image{width:100%;height:100%;object-fit:cover;object-position:top}.member-info{display:flex;flex-direction:column;flex:1;width:100%}.member-name{font-size:1rem;font-weight:600;color:#0f172a;margin-bottom:.4rem;line-height:1.3;min-height:2.6rem;display:flex;align-items:center;justify-content:center}.member-link{text-decoration:none;color:inherit;transition:color .2s}.member-link:hover{color:#2563eb}.member-title{font-size:.8rem;color:#334155;margin-bottom:.5rem;font-weight:500;min-height:3rem;display:flex;align-items:flex-start;justify-content:center;line-height:1.3}.member-department-badge{display:inline-block;padding:.2rem .5rem;border-radius:9999px;font-size:.65rem;font-weight:600;text-transform:uppercase;letter-spacing:.025em;margin-top:auto;align-self:center}.support-section{margin-top:4rem;padding-top:3rem;border-top:1px solid #e2e8f0}.support-header{text-align:center;margin-bottom:2.5rem}.support-header h2{font-size:2.5rem;color:#1e293b;margin-bottom:.75rem}.support-header p{font-size:1.1rem;color:#64748b}.support-grid{display:grid;grid-template-columns:repeat(2,1fr);gap:2rem;max-width:1000px;margin:0 auto}@media(max-width:768px){.support-grid{grid-template-columns:1fr}}.support-card{display:flex;background:#fff;border-radius:16px;padding:2rem;text-decoration:none;color:inherit;transition:all .3s ease;position:relative;overflow:hidden;border:1px solid #e2e8f0}.support-card:before{content:"";position:absolute;top:0;left:0;right:0;height:4px;transition:height .3s ease}.support-card:hover{transform:translateY(-4px);box-shadow:0 20px 25px -5px #0000001a,0 8px 10px -6px #0000001a}.support-card:hover:before{height:6px}.support-card-nicu:before{background:linear-gradient(90deg,#0ea5e9,#38bdf8)}.support-card-nicu .support-card-icon{background:linear-gradient(135deg,#e0f2fe,#bae6fd);color:#0284c7}.support-card-nicu:hover{border-color:#0ea5e9}.support-card-grant:before{background:linear-gradient(90deg,#10b981,#34d399)}.support-card-grant .support-card-icon{background:linear-gradient(135deg,#d1fae5,#a7f3d0);color:#059669}.support-card-grant:hover{border-color:#10b981}.support-card-icon{flex-shrink:0;width:64px;height:64px;border-radius:12px;display:flex;align-items:center;justify-content:center;margin-right:1.5rem}.support-card-icon svg{width:32px;height:32px}.support-card-content{flex:1}.support-card-content h3{font-size:1.25rem;font-weight:700;color:#0f172a;margin-bottom:.5rem;line-height:1.3}.support-card-content p{font-size:.95rem;color:#64748b;line-height:1.6;margin-bottom:.75rem}.grant-highlight{margin-bottom:.5rem!important}.grant-badge{display:inline-block;background:linear-gradient(135deg,#10b981,#059669);color:#fff;font-size:.75rem;font-weight:700;padding:.35rem .75rem;border-radius:9999px;text-transform:uppercase;letter-spacing:.05em;box-shadow:0 2px 4px #10b9814d}.support-card-link{display:inline-flex;align-items:center;gap:.5rem;font-size:.9rem;font-weight:600;color:#3b82f6;transition:gap .2s ease}.support-card:hover .support-card-link{gap:.75rem}.support-card-link svg{width:16px;height:16px}.acknowledgment-banner{margin-top:3rem;background:linear-gradient(135deg,#fef3c7,#fde68a,#fcd34d);border-radius:16px;padding:1.75rem 2rem;position:relative;overflow:hidden}.acknowledgment-banner:before{content:"";position:absolute;top:-50%;right:-20%;width:300px;height:300px;background:radial-gradient(circle,rgba(251,191,36,.3) 0%,transparent 70%);pointer-events:none}.acknowledgment-content{display:flex;align-items:center;gap:1rem;position:relative;z-index:1}.acknowledgment-icon{flex-shrink:0;width:40px;height:40px;color:#b45309}.acknowledgment-content p{font-size:1rem;color:#78350f;line-height:1.6;margin:0}.acknowledgment-content strong{color:#92400e}@media(max-width:640px){.support-card{flex-direction:column;text-align:center}.support-card-icon{margin:0 auto 1rem}.acknowledgment-content{flex-direction:column;text-align:center}}